Multi-purpose anti-itch treatment

摘要

There is disclosed a formulation of a transdermal skin treatment effective in inhibition of itch sensation. In an embodiment, the formulation includes a solvent mixture of alcohols, glycols and water combined to provide a solubility parameter between 20 Pa0.5 and 40 Pa0.5, the solvent mixture having an average normal boiling temperature of at least 100° C., the solvent mixture having at least 0.04 mols/liter of multivalent cations, the solvent mixture containing at least one local anesthetic, and the solvent mixture having pH exceeding 8.0, with a thixotropic flow characteristic accomplished by an organic gellant. Other embodiments are also disclosed.

主权项

1. A formulation of a transdermal skin treatment effective in inhibition of itch sensation, the formulation comprising:
a solvent mixture of alcohols, glycols and water combined to provide a solubility parameter between 20 Pa0.5 and 40 Pa0.5, the solvent mixture having an average normal boiling temperature of at least 100° C., the solvent mixture having at least 0.04 mols/liter of multivalent cations, the solvent mixture containing at least one local anesthetic, and the solvent mixture having pH exceeding 8.0, with a thixotropic flow characteristic accomplished by an organic gellant, a colloidal oat flour, and the multivalent cations configured for delivery by the solvent mixture to allow the multivalent cations to penetrate an epidermis barrier with greater penetration than water so as to deliver the multivalent cations to nerve endings for the transdermal skin treatment effective in inhibition of itch sensations.