发明名称 5,8-difluoro-4-(2-(4-(heteroaryloxy)-phenyl)ethylamino)quinazolines and their use as agrochemicals
摘要 The present disclosure relates to compounds of Formula 1,5,8-difluoro-4-(2-(4-(heteroaryloxy)phenyl)ethylamino)quinazolines, and their use as agrochemicals and animal health products.;
申请公布号 US9000162(B2) 申请公布日期 2015.04.07
申请号 US201213621611 申请日期 2012.09.17
申请人 Dow AgroSciences LLC 发明人 Brewster William K.;Klittich Carla J. R.;Yao Chenglin;Zhu Yuanming;Rieder Brent J.
分类号 C07D239/88;C07D239/94;C07D401/12;C07D403/12 主分类号 C07D239/88
代理机构 Faegre Baker Daniels LLP 代理人 Arnett C. W.;Faegre Baker Daniels LLP
主权项 1. A method of treatment for fungi, insects, and nematodes, comprising the step of: applying a compound according to Formula (I), to a plant or animal in need thereof, the compound of Formula I is as follows:wherein: R represents H, CH3, or a heterocycle selected from the group consisting of pyridinyl, pyrazinyl, pyrimidinyl, and pyridazinyl wherein the heterocycle may be optionally substituted with one or more groups selected from halo, lower alkyl, lower alkenyl, lower alkynyl, lower alkoxy, haloalkyl, haloalkoxy, NO2, CN, lower alkoxycarbonyl, and lower alkyl-SOq, when q is an integer from 0 to 2; Z represents a C—C single bond, CH2, NH, O, S, —CH2O—, or —OCH2—; m is 4; R1 are independently H, halo, lower alkyl, lower alkenyl, lower alkynyl, hydroxy, lower alkoxy, haloalkyl, haloalkoxy, NO2, CN, lower alkoxycarbonyl, mercapto, or lower alkylthio; Y is a C—C single bond, C(R7n)O or C(R7n); n is 2; R2 are independently H or lower alkyl; R7 are independently H or lower alkyl; X is NR3 or O, where R3 is selected from H, lower alkyl, lower alkyl-carbonyl, lower alkoxycarbonyl, hydroxy, lower alkoxy, lower alkyl-SOq, phenyl-SOq or substituted phenyl-SOq when q is an integer from 0 to 2; and R4 is H or F;with the proviso that when Y is C(R7n), R2n and one of R1 may be taken together to form a compound of formula (II)
地址 Indianapolis IN US