| 发明名称 |
Cancer prognosis by determining phosphorylation of a Xom polypeptide |
| 摘要 |
Disclosed are composition and methods for treating development-related disorders. Also disclosed are diagnosis methods, prognosis methods, and drug screening methods. |
| 申请公布号 |
US8993227(B2) |
申请公布日期 |
2015.03.31 |
| 申请号 |
US201313859285 |
申请日期 |
2013.04.09 |
| 申请人 |
|
发明人 |
Zhu Zhenglun;Gao Hong |
| 分类号 |
C12Q1/00;C12Q1/68;G01N33/53;C07K14/46;C07K14/47;A61K38/00 |
主分类号 |
C12Q1/00 |
| 代理机构 |
Cesari and McKenna, LLP |
代理人 |
Cesari and McKenna, LLP |
| 主权项 |
1. A method of assessing a human subject's cancer prognosis, the method comprising:
obtaining a cell from the subject; determining in the cell the level of a kinase activity, wherein the kinase activity is phosphorylation of Ser140 or Ser144 of an exogenous Xom polypeptide; whereby the subject is determined to have a bad prognosis if the level of the kinase activity is higher than a control level. |
| 地址 |
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