Selective inhibitors of translesion DNA replication

摘要

An agent for inhibiting translesion DNA replication comprises a non-natural adenine ribose analog represented by those as set forth in FIG. 1.

主权项

1. A method of monitoring DNA damage, comprising:
treating cells of a patient with: 5 phenyl-indolyl-2′deoxyriboside, a phosphate thereof, or a pharmaceutically acceptable salt thereof; and determining the amount of the agent incorporated into the DNA of the cells.