A COMPOSITION FOR PREVENTION AND TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE

摘要

The present invention relates to a composition for effectively preventing and treating non-alcoholic fatty liver disease, which is caused by the accumulation of fatty acid in the liver due to excessive intake of nutrients or metabolic syndrome regardless of alcohol intake. The composition contains an Aronia melanocarpa extract and a Silybum marianum extract. The composition of the present invention can greatly improve an increase in the weight of the liver, the accumulation of liver neutral fat, an increase in a serum ALT concentration, a reduction in liver SOD activity, a reduction in total antioxidative activity of the liver, and the like, in experimental animals which are grown with a high fat diet for a long period of time. The fatty liver disease caused by a high fat diet in the experimental animals shows similar pathological and immunological findings to human non-alcoholic fatty liver disease, and thus the composition of the present invention can be provided as a great pharmaceutical agent or health supplement foods used to prevent and treat non-alcoholic fatty liver disease.