摘要 |
The present invention addresses the problem of providing an antibody titer-increasing agent, such as an adjuvant, capable of sustaining an effect achieved by, for example, vaccination, which is an antibody titer-increasing agent such as an adjuvant that is safe, convenient and economical and can be easily taken irrespective of age, and a method for manufacturing the same. A method for increasing an antibody titer and a method for enhancing the effect of a vaccine, each method comprising using Lactobacillus delbrueckii subspecies bulgaricus OLL1073R-1 or a culture thereof; and an antibody titer-increasing agent such as an adjuvant that comprises Lactobacillus delbrueckii subspecies bulgaricus OLL1073R-1 or a culture thereof. |
申请人 |
MEIJI CO., LTD.;JUNTENDO UNIVERSITY |
发明人 |
MAKINO, SEIYA;HENMI, JUN;KANO, HIROSHI;ASAMI, YUKIO;IKEGAMI, SHUJI;ITOU, HIROYUKI;SUZUKI, YOSHIO;KAWAI, SACHIO;SAWAKI, KEISUKE;OKUMURA, YASUSHI;NAGAOKA, ISAO;TAKEDA, KAZUYOSHI |