发明名称 |
ADMINISTRATION OF KYNURENINE DEPLETING ENZYMES FOR TUMOR THERAPY |
摘要 |
Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids. |
申请公布号 |
WO2015031771(A2) |
申请公布日期 |
2015.03.05 |
申请号 |
WO2014US53437 |
申请日期 |
2014.08.29 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
GEORGIOU, GEORGE;STONE, EVERETT |
分类号 |
C12N9/14;A61K35/14;A61K38/46 |
主分类号 |
C12N9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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