发明名称 COMPLEXES OF GERMANIUM WITH AMINO ACIDS AND CARBOXYLIC ACIDS AND METHOD FOR PREPARING SAME
摘要 The invention relates to complex compounds of germanium with amino acids and carboxylic acids of the general formula Ge[OH] a [AA] b [CA] c (I), where AA is an amino acid, CA is a carboxylic acid, a = 0-3, b = 1-3, c = 0-3, and 1<b+c<4, wherein AA and CA in the complex can be identical or different, and to a method for preparing the same. The method consists in preparing an aqueous suspension of germanium dioxide, adding an amino acid and a carboxylic acid to the aqueous suspension of germanium oxide produced, heating the mixture produced with agitation at a temperature of 40-100°C for 2-14 hours with subsequent filtering, removal of the water and production of a complex in solid form. The method makes it possible to prepare stable complex compounds with a controllable composition and a controllable ratio of germanium to amino acid and carboxylic acid which are stable in solid form and can be used in medicine.
申请公布号 EP2808330(A4) 申请公布日期 2015.02.25
申请号 EP20120866873 申请日期 2012.11.09
申请人 OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU "WDS FARMA" 发明人 ISAEV, ALEXANDR DMITRIEVICH;MANASHEROV, TAMAZ OMAROVICH;AMBROSOV, IGOR VALERIEVICH;MATELO, SVETLANA KONSTANTINOVNA
分类号 C07F7/30;A61K31/28 主分类号 C07F7/30
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