发明名称 |
LOW -MOLECULAR -WEIGHT BIOTECHNOLOGICAL CHONDROITIN 6 - SULPHATE FOR PREVENTION OF OSTEOARTHRITIS. |
摘要 |
Disclosed is a low-molecular-weight (1000-5000 daltons) chondroitin sulphate (CS) produced by chemical sulphation and subsequent depolymerisation of a non-sulphated chondroitin backbone obtained with biotechnology techniques. The CS described is substantially monosulphated, mainly at the 6-position, with very little sulphation at the 4-position, and with a mono/disulphated disaccharide ratio and charge density similar to those of natural CS. Said biotechnological chondroitin 6-sulphate (C6S) is useful in the treatment and prevention of osteoarthritis and in acute and chronic inflammatory processes. |
申请公布号 |
MX2014014115(A) |
申请公布日期 |
2015.02.24 |
申请号 |
MX20140014115 |
申请日期 |
2013.05.22 |
申请人 |
GNOSIS S.P.A. |
发明人 |
BIANCHI, DAVIDE;VALETTI, MARCO;BAZZA, PAOLA;MIRAGLIA, NICCOLÒ;VALOTI, ERMANNO;BUSIELLO, IMMACOLATA;TRENTIN, ANTONELLA;TRILLI, ANTONIO;AGOSTINETTO, MARCO |
分类号 |
A61P19/02;A61K31/375;A61K31/726;A61K31/737;A61K45/06;A61P19/00;C08B37/00 |
主分类号 |
A61P19/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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