Compounds

摘要

This invention relates to compounds of formula I,;
their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as medicaments for the treatment and/or prevention of inflammatory diseases and associated conditions such as inflammatory/nociceptive pain.
;A, M, R1, R2, R7, Ra, Rb, Q3, Q4, Q6, Z2, Z4, Z5, Z6 and W have meanings given in the description.

主权项

1. A compound selected from the following compounds:#Structure123457891011121314151617181920212223242526272829303132333435363738394041424344454647484950515253545556575859606162636465666768697071727778798081828384858687888990919293949596979899100101102103104105106107108109110111112113114115116117118119120121122123124125126127128129130131132133134135136137138139140141142143144145146147148149150151152153154155156157158159160161162163164165166167168169170171172173174175176177179180181or a pharmaceutically acceptable salt thereof.