| 发明名称 | <i>N</i>-demethyase genes and uses thereof | ||
| 摘要 | The invention provides isolated nucleic acid encoding one or more gene products that allow for degradation of caffeine and related structures, and for preparation of intermediates in that catabolic pathway. Further provided are methods of using one or more of those gene products. | ||
| 申请公布号 | US8951752(B2) | 申请公布日期 | 2015.02.10 |
| 申请号 | US201214344037 | 申请日期 | 2012.10.18 |
| 申请人 | University of Iowa Research Foundation | 发明人 | Subramanian Venkiteswaran;Louie Michael Tai-Man;Summers Ryan |
| 分类号 | C12Q1/34;C12N15/00;C12N1/20;C12N9/14;C07K1/00;C07H21/04;C12N9/02;C12P17/18;C12Q1/26 | 主分类号 | C12Q1/34 |
| 代理机构 | Schwegman Lundberg & Woessner, P.A. | 代理人 | Schwegman Lundberg & Woessner, P.A. |
| 主权项 | 1. An isolated chimeric polypeptide which comprises a N-demethylase or a reductase having at least 96% amino acid sequence identity to a polypeptide encoded by a polynucleotide comprising SEQ ID NO: 37, or having at least 85% identity to a polypeptide encoded by a polynucleotide comprising SEQ ID NO:38 or 39 or SEQ ID NO:43. | ||
| 地址 | Iowa City IA US | ||