发明名称 SUPER-RESOLUTION MICROSCOPE AND MODULATION OPTICAL ELEMENT
摘要 A super-resolution microscope includes a modulation optical element (10) that is disposed in an illumination optical system along a light path traveled by first illumination light and second illumination light and spatially modulates the second illumination light. In the modulation optical element (10), a plurality of optical substrates exhibiting anisotropy in a refractive index distribution are joined in a coplanar manner, and at least two of the optical substrates have a different refractive index with respect to a polarization direction of the second illumination light.
申请公布号 US2015034810(A1) 申请公布日期 2015.02.05
申请号 US201414452369 申请日期 2014.08.05
申请人 OLYMPUS CORPORATION 发明人 IKETAKI Yoshinori
分类号 G02B21/00;G02B21/06 主分类号 G02B21/00
代理机构 代理人
主权项 1. A super-resolution microscope for observing a sample including a molecule having at least two excited quantum states, the super-resolution microscope comprising: an illumination optical system configured to collect first illumination light and second illumination light on the sample by partially spatially overlapping the lights to irradiate the sample, the first illumination light being for exciting the molecule from a stable state to a first quantum state and the to second illumination light being for causing the molecule to transition further to another quantum state; a scanning unit configured to scan the sample by displacing the sample relative to the first illumination light and the second illumination light; a detection unit configured to detect a light response signal generated by the sample due to irradiation with the first illumination light and the second illumination light; and a modulation optical element disposed in the illumination optical system along a light path traveled by the first illumination light and the second illumination light and configured to spatially modulate the second illumination light, wherein in the modulation optical element, a plurality of optical substrates exhibiting anisotropy in a refractive index distribution are joined in a coplanar manner, and at least two of the optical substrates have a different refractive index with respect to a polarization direction of the second illumination light.
地址 Tokyo JP