| 发明名称 | Polynucleotides encoding BMP-ALK3 antagonists | ||
| 摘要 | In certain aspects, the present invention provides compositions and methods for promoting bone growth and increasing bone density and strength. In certain embodiments, the present invention provides ALK3 polypeptides, including ALK3-Fc fusion proteins. | ||
| 申请公布号 | US8945877(B2) | 申请公布日期 | 2015.02.03 |
| 申请号 | US201213724546 | 申请日期 | 2012.12.21 |
| 申请人 | Acceleron Pharma, Inc. | 发明人 | Seehra Jasbir |
| 分类号 | C12N15/11;C12N15/63;C12N5/10;C12N1/21;C07K16/28;C07K14/51;C07K14/71;C07K16/22;A61K38/00 | 主分类号 | C12N15/11 |
| 代理机构 | Ropes & Gray LLP | 代理人 | Ropes & Gray LLP |
| 主权项 | 1. An isolated polynucleotide comprising a coding sequence for a polypeptide comprising the amino acid sequence of SEQ ID NO:7. | ||
| 地址 | Cambridge MA US | ||