发明名称 SUBSTITUTED ISOQUINOLINONES AND QUINAZOLINONES
摘要 <p>The invention relates to substituted nitrogen containing bicyclic heterocycles of the formula (I) wherein Z is CH2 or N-R4 and X, R1, R2, R4, R6, R7 and n are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of MDM2 and/or MDM4, or variants thereof.</p>
申请公布号 SI2516009(T1) 申请公布日期 2015.01.30
申请号 SI20100030821T 申请日期 2010.12.21
申请人 NOVARTIS AG 发明人 BERGHAUSEN JOERG;BUSCHMANN NICOLE;FURET PASCAL;GESSIER FRANCOIS;HERGOVICH LISZTWAN JOANNA;HOLZER PHILIPP;JACOBY EDGAR;KALLEN JOERG;MASUYA KEIICHI;PISSOT SOLDERMANN CAROLE;REN HAIXIA;STUTZ STEFAN
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