| 发明名称 |
AURORA AND FLT3 KINASES MODULATORS |
| 摘要 |
The invention provides a compound having the formula (1):;;and salts thereof; wherein:
R1 is hydrogen or C1-2 alkyl; and
R2, R3 and R4 are the same or different and each is selected from hydrogen, C1-2 alkyl, fluorine, chlorine, C1-2 alkoxy and trifluoromethyl, provided that no more than two of R2, R3 and R4 are other than hydrogen.
;Also provided are pharmaceutical compositions containing the compounds and their use in medicine, and in particular in the treatment of cancer. |
| 申请公布号 |
US2015018367(A1) |
申请公布日期 |
2015.01.15 |
| 申请号 |
US201314376729 |
申请日期 |
2013.02.04 |
| 申请人 |
SAREUM LIMITED |
发明人 |
Reader John Charles |
| 分类号 |
C07D413/14;A61K45/06;A61K31/496 |
主分类号 |
C07D413/14 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound having the formula (1): and salts thereof; wherein: R1 is hydrogen or C1-2 alkyl; and R2, R3 and R4 are the same or different and each is selected from hydrogen, C1-2 alkyl, fluorine, chlorine, C1-2 alkoxy and trifluoromethyl, provided that no more than two of R2, R3 and R4 are other than hydrogen. |
| 地址 |
Cambridge GB |
