| 发明名称 |
Delayed-release glucocorticoid treatment of rheumatoid disease |
| 摘要 |
Provided are methods for the treatment of a rheumatic disease, such as rheumatoid arthritis, ankylosating spondylitis and/or polymyalgia rheumatic, by administering a delayed-release dosage form of a glucocorticoid to a subject in need thereof wherein the treatment is administered once daily for at least about two weeks. Also provided are methods for the treatment of osteoarthritis by administering a delayed-release dosage form of a glucocorticoid to a subject in need thereof wherein the treatment is administered once daily for at least about two weeks. |
| 申请公布号 |
US8920838(B2) |
申请公布日期 |
2014.12.30 |
| 申请号 |
US201313860015 |
申请日期 |
2013.04.10 |
| 申请人 |
Horizon Pharma AG |
发明人 |
Schaeffler Achim |
| 分类号 |
A61K9/22;A61K9/48;A61P19/02;C07J5/00;A61K45/06;A61K31/573;A61K9/28 |
主分类号 |
A61K9/22 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for the treatment of a patient suffering from signs and symptoms of an underlying rheumatic disease and/or osteoarthritis, which comprises administering to said patient an effective amount of prednisone contained in a delayed-release dosage form,
wherein said treatment is administered once daily for at least about two weeks, wherein said patient has previously undergone treatment with an oral immediate release dosage form of a glucocorticoid and was refractory to said treatment with said oral immediate release dosage form of a glucocorticoid, and wherein the delayed release dosage form is a tablet or a capsule. |
| 地址 |
Reinach CH |
