发明名称 SURFACE OF SUBSTRATE ONTO WHICH NON-SPECIFIC ADSORPTION IS RESTRAINED
摘要 A substrate surface on which either a substance to detect analyte or an analyte per se is immobilized, which surface is formed by a treatment of substrate surface with a liquid which contains uncrosslinked polymer based on polyethylene glycol chain segment, said treatment conducted either simultaneously with the immobilization of said substance or analyte or after said substance or analyte has been immobilized on said surface. The non-specific adsorption of impurity protein or the like which is co-existent in sample for assay is significantly restrained.
申请公布号 US2014378346(A1) 申请公布日期 2014.12.25
申请号 US201414459888 申请日期 2014.08.14
申请人 JSR Corporation 发明人 NAGASAKI Yukio;TAKAHASHI Tadahito;KATAOKA Kazunori;ABOSHI Fumiko;KATO Miki;JOMURA Tomoko;KOBAYASHI Hiroshi;KATSUYAMA Yoshinori;NAKAMAE Masami
分类号 C12Q1/68;G01N27/327;G01N33/543 主分类号 C12Q1/68
代理机构 代理人
主权项 1. A substrate surface on which either a substance to detect analyte or an analyte per se is immobilized, which surface is formed by a treatment of substrate surface with a liquid which contains uncrosslinked polymer based on polyethylene glycol chain segment, said treatment conducted either simultaneously with the immobilization of said substance or analyte or after said substance or analyte has been immobilized on said surface, wherein the substrate surface is selected from the group consisting of electrochemical sensor surface, surface plasmon sensor surface, quartz sensor surface, microplate surface for solid phase enzyme-linked immunoassay (ELISA), plastic film surface for protein blotting or nucleic acid blotting, microarray surface for the hybridization of nucleic acid, gold particle surface, semiconductor nano particle surface, silica particle surface, fine porous particle surface and particle surface of latex which contains one of the above-mentioned particles.
地址 Tokyo JP