发明名称 |
COMBINATIONS OF BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF |
摘要 |
<p>This invention relates to a method of treating a disorder modulated, mediated or affected by the estrogen receptor in a subject comprising administering to the subject a specific benzopyran (in the form of a mixture of S-C2 and R-C2 diastereomers or its pure S-diastereomer) in combination with an agent selected from the group consisting of an mTOR inhibitor, a CDK 4/6 inhibitor, a PI3 Kinase inhibitor, a taxane, an antimetabolite, and an antitumor antibiotic.</p> |
申请公布号 |
WO2014203129(A1) |
申请公布日期 |
2014.12.24 |
申请号 |
WO2014IB62176 |
申请日期 |
2014.06.12 |
申请人 |
OLEMA PHARMACEUTICALS, INC. |
发明人 |
KUSHNER, PETER, J.;GALLAGHER, LESLIE, HODGES;HARMON, CYRUS, L.;MYLES, DAVID, C. |
分类号 |
A61K45/06;A61K31/337;A61K31/4025;A61K31/436;A61K31/513;A61K31/519;A61K31/5377;A61K31/704;A61P35/00 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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