| 发明名称 |
Prame derived peptides and immunogenic compositions comprising these |
| 摘要 |
The invention relates to a peptide having a length of no more than 100 amino acids and comprising at least 19 contiguous amino acids from the amino acid sequence of the human PRAME protein, wherein the peptide comprises at least one HLA class II epitope and at least one HLA class I epitope from the amino acid sequence of the human PRAME protein and to its use as such or in a composition as a medicament for the treatment and/or prevention of cancer. |
| 申请公布号 |
US2014348862(A1) |
申请公布日期 |
2014.11.27 |
| 申请号 |
US201313945335 |
申请日期 |
2013.07.18 |
| 申请人 |
Academisch Ziekenhuis Leiden h.o.d.n. LUMC |
发明人 |
Kessler Jan;Griffioen Marieke;Melief Cornelis Johannes Maria;Drijfhout Jan Wouter |
| 分类号 |
C07K14/47 |
主分类号 |
C07K14/47 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A peptide having a length of no more than 100 amino acids and comprising at least 19 contiguous amino acids from the amino acid sequence of the human PRAME protein, wherein the peptide comprises at least one HLA class II epitope and at least one HLA class I epitope from the amino acid sequence of the human PRAME protein. |
| 地址 |
Leiden NL |
