摘要 |
Esterified cellulose ethers comprising groups of formula -C(O) - CHR' - CHR"- COOA, wherein, R' and R" are hydrogen or (- S)m (- R1)n - R2, wherein R1 is a hydrocarbon group having 1 to 4 carbon atoms, R2 is an optionally substituted 5- or 6-membered cyclic group, m and n each independently are 0 or 1, and A is hydrogen or a cation, with the proviso that in each group CHR' - CHR" one of R' and R" is hydrogen and the other one is (- S)m (- R1)n - R2, are useful as excipients for maintaining the concentration of poorly water-soluble drugs in aqueous liquids at supersaturation levels. |