发明名称 Use of the endoglycosidase endos for treating immunoglobulin G mediated diseases
摘要 The invention provides use of an EndoS polypeptide, or a polynucleotide encoding an EndoS polypeptide, in the manufacture of a medicament for the treatment or prevention of a disease or condition mediated by IgG antibodies.
申请公布号 US8889128(B2) 申请公布日期 2014.11.18
申请号 US200712518855 申请日期 2007.12.12
申请人 Hansa Medical AB 发明人 Björck Lars;Collin Mattias;Olsén Arne;Holmdahl Rikard;Nandakumar Kutty Selva;Shannon Oonagh
分类号 A61K38/48;A61K39/02 主分类号 A61K38/48
代理机构 Kilpatrick Townsend & Stockton LLP 代理人 Kilpatrick Townsend & Stockton LLP
主权项 1. A method of treating or preventing a disease or condition mediated by IgG antibodies in a subject in need thereof, wherein the method of treating the disease or condition comprises administering to the subject a therapeutically effective amount of the polypeptide consisting of SEQ ID NO: 1 and wherein the method of preventing the disease or condition comprises administering to the subject a prophylactically effective amount of the polypeptide consisting of SEQ ID NO: 1.
地址 Lund SE