发明名称 |
Use of the endoglycosidase endos for treating immunoglobulin G mediated diseases |
摘要 |
The invention provides use of an EndoS polypeptide, or a polynucleotide encoding an EndoS polypeptide, in the manufacture of a medicament for the treatment or prevention of a disease or condition mediated by IgG antibodies. |
申请公布号 |
US8889128(B2) |
申请公布日期 |
2014.11.18 |
申请号 |
US200712518855 |
申请日期 |
2007.12.12 |
申请人 |
Hansa Medical AB |
发明人 |
Björck Lars;Collin Mattias;Olsén Arne;Holmdahl Rikard;Nandakumar Kutty Selva;Shannon Oonagh |
分类号 |
A61K38/48;A61K39/02 |
主分类号 |
A61K38/48 |
代理机构 |
Kilpatrick Townsend & Stockton LLP |
代理人 |
Kilpatrick Townsend & Stockton LLP |
主权项 |
1. A method of treating or preventing a disease or condition mediated by IgG antibodies in a subject in need thereof, wherein the method of treating the disease or condition comprises administering to the subject a therapeutically effective amount of the polypeptide consisting of SEQ ID NO: 1 and wherein the method of preventing the disease or condition comprises administering to the subject a prophylactically effective amount of the polypeptide consisting of SEQ ID NO: 1. |
地址 |
Lund SE |