| 主权项 |
1. A composition comprising an isolated mixture of cytotoxic anti-CD20 antibody molecules produced in a transgenic avian, wherein the antibody molecules comprise a heavy chain and a light chain whose amino acid sequences set forth from position 23 to position 235 of SEQ ID NO:1 and from position 20 to position 470 of SEQ ID NO: 2, respectively, wherein the isolated mixture of cytotoxic anti-CD20 antibody molecules exhibit an increased level of antibody-dependent cell-mediated cytotoxicity (ADCC) as compared to that of anti-CD20 antibody molecules produced in CHO cells and having the same amino acid sequence. |
