Syringe-based whispering gallery mode microresonator microfluidic biochem sensor

摘要

A syringe-based whispering gallery mode sensor includes a syringe including an assembly provided its needle, the assembly including (1) an optical carrier having a reflective distal end, and (2) at least one resonator coupled with the optical carrier. This sensor may be provided in a system including a light source, a light detector, and a data analysis component. A method for determining the presence or concentration of a target substance in body fluid may be performed using such a system.

主权项

1. A sensor for determining the presence or concentration of a target substance in a body fluid, the sensor comprising:
a) a syringe including
1) a needle,2) a barrel fluidly coupled with the needle, and3) a plunger adapted to fit within and be slideable within the barrel; and b) an assembly provided within the needle of the syringe and including
1) an optical carrier having a reflective distal end, and2) at least one resonator coupled with the optical carrier and provided with receptors adapted to selectively capture the target substance.