| 发明名称 | Implantable delivery vehicle for ocular delivery of muscarinic antagonists | ||
| 摘要 | The present invention provides compositions and methods for treating ocular disorders such as myopia. | ||
| 申请公布号 | US8883214(B2) | 申请公布日期 | 2014.11.11 |
| 申请号 | US201013144065 | 申请日期 | 2010.01.11 |
| 申请人 | The Regents of the University of California | 发明人 | Wildsoet Christine F.;Su James;Healy Kevin E. |
| 分类号 | A61K9/50;A61K47/32;A61L27/52;A61L27/54;A61K9/00;A61K9/06 | 主分类号 | A61K9/50 |
| 代理机构 | Bozicevic, Field & Francis LLP. | 代理人 | Borden Paula A.;Bozicevic, Field & Francis LLP. |
| 主权项 | 1. A method of treating high myopia in an individual having high myopia, the method comprising administering to the individual an effective amount of a muscarinic antagonist-containing biodegradable hydrogel, wherein the hydrogel is selected from the groups consisting of a bifunctional block copolymer of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO), a poly(N-isopropylacrylamide)-based hydrogel, or a poly(N-isopropylacrylamide)-acrylic acid copolymer, and poly(2-hydroxyethylene methacrylate), wherein the muscarinic antagonist-containing hydrogel is administered by intraorbital injection. | ||
| 地址 | Oakland CA US | ||