| 摘要 |
A process is described wherein, using 17α-(3-hydroxyprapyl)-6&bgr;,7&bgr;,15&bgr;,16&bgr;- dimethylene-5&bgr;-androstane-3&bgr;,5,17&bgr;-triol (III) as starting product, there is obtained 3&bgr;,5-dihydroxy-6&bgr;,7&bgr;,15&bgr;,16&bgr;-dimethylene-5&bgr;-17α-pregna-21, 17-carbolactone (I), a useful intermediate in the synthesis of the compound drospirenone, having contraceptive action: (Formula III & I) (III) (I) |
