| 发明名称 |
HUMAN GROWTH HORMONE RECEPTOR ANTAGONIST ANTIBODIES AND METHODS OF USE THEREOF |
| 摘要 |
<p>The present invention provides antagonizing antibodies that bind to growth hormone receptor (GHR). The invention further relates to therapeutic methods for use of these antibodies to reduce IGF-1 levels and/or for the treatment and/or prevention of diseases associated with excessive IGF-1, including treatment of acromegaly, gigantism, cancer, diabetic nephropathy, arthritis, and lung inflammation.</p> |
| 申请公布号 |
SG11201402828X(A) |
申请公布日期 |
2014.10.30 |
| 申请号 |
SGX11201402828 |
申请日期 |
2012.12.10 |
| 申请人 |
RINAT NEUROSCIENCE CORP. |
发明人 |
SIEBEL, SARA IVA;PASCUA, EDWARD DERRICK;LIN, CHIA-YANG;CHAPARRO RIGGERS, JAVIER FERNANDO |
| 分类号 |
C07K16/28;A61K39/395;A61P35/00 |
主分类号 |
C07K16/28 |
| 代理机构 |
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