发明名称 HETEROCYCLYL DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS
摘要 The present invention relates to phenyl-substituted heterocyclyl derivatives of the formula (I), wherein Z, n, m, R1, R2, R3, R4, R5, R6, R7 and R8 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin D2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.
申请公布号 EP2794563(A1) 申请公布日期 2014.10.29
申请号 EP20120823031 申请日期 2012.12.20
申请人 ACTELION PHARMACEUTICALS LTD. 发明人 AISSAOUI, HAMED;BOSS, CHRISTOPH;RICHARD-BILDSTEIN, SYLVIA;SIEGRIST, ROMAIN
分类号 C07D209/44;A61K31/47;C07D217/06;C07D223/06;C07D223/16;C07D401/06;C07D401/12;C07D405/06;C07D413/06;C07D417/06 主分类号 C07D209/44
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