发明名称 Methods for inhibiting peritoneal dissemination of cancer cells
摘要 A pharmaceutical composition for treating or preventing peritoneal dissemination is provided. The pharmaceutical composition includes an effective dose of connective tissue growth factor (CTGF) and a pharmaceutically acceptable carrier thereof.
申请公布号 US8871721(B2) 申请公布日期 2014.10.28
申请号 US201213409325 申请日期 2012.03.01
申请人 发明人 Kuo Min-Liang;Lin Been-Ren;Chang Cheng-Chi;Chen Chiung-Nine
分类号 A61K38/18;A61P35/00;G01N33/574;G01N33/50 主分类号 A61K38/18
代理机构 Porzio, Bromberg & Newman, P.C. 代理人 Porzio, Bromberg & Newman, P.C.
主权项 1. A method for inhibiting a peritoneal dissemination of a cancer cell of a patient, the cancer cell being one selected from a group consisting of a gastric cancer, a small intestine cancer, a colon cancer, a rectal cancer, an ovary cancer, an appendiceal cancer and a pancreatic cancer, comprising a step of: administering to the patient an effective dose pharmaceutical composition, comprising a connective tissue growth factor (CTGF) and/or an active fragment thereof, wherein the CTGF and/or the active fragment thereof inhibits the cancer cell adhering to the peritoneal cavity or the formation of a peritoneal nodule, and the pharmaceutical composition is administered in one of two ways: once per two days for at least 14 days and once per day for at least 7 days.
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