发明名称 |
Methods for inhibiting peritoneal dissemination of cancer cells |
摘要 |
A pharmaceutical composition for treating or preventing peritoneal dissemination is provided. The pharmaceutical composition includes an effective dose of connective tissue growth factor (CTGF) and a pharmaceutically acceptable carrier thereof. |
申请公布号 |
US8871721(B2) |
申请公布日期 |
2014.10.28 |
申请号 |
US201213409325 |
申请日期 |
2012.03.01 |
申请人 |
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发明人 |
Kuo Min-Liang;Lin Been-Ren;Chang Cheng-Chi;Chen Chiung-Nine |
分类号 |
A61K38/18;A61P35/00;G01N33/574;G01N33/50 |
主分类号 |
A61K38/18 |
代理机构 |
Porzio, Bromberg & Newman, P.C. |
代理人 |
Porzio, Bromberg & Newman, P.C. |
主权项 |
1. A method for inhibiting a peritoneal dissemination of a cancer cell of a patient, the cancer cell being one selected from a group consisting of a gastric cancer, a small intestine cancer, a colon cancer, a rectal cancer, an ovary cancer, an appendiceal cancer and a pancreatic cancer, comprising a step of: administering to the patient an effective dose pharmaceutical composition, comprising a connective tissue growth factor (CTGF) and/or an active fragment thereof, wherein the CTGF and/or the active fragment thereof inhibits the cancer cell adhering to the peritoneal cavity or the formation of a peritoneal nodule, and the pharmaceutical composition is administered in one of two ways: once per two days for at least 14 days and once per day for at least 7 days. |
地址 |
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