Tobacco chewing gum formulation

摘要

A chewing gum formulation including tobacco particles and a gum base, where the gum base includes one or more hydrophobic gum base polymers, and where the tobacco particles are made from tobacco leaves. The amount of tobacco particles is between 0.5 and 30% by weight of the chewing gum formulation, and nicotine is released from the tobacco particles when chewing the chewing gum formulation.

主权项

1. A chewing gum formulation comprising tobacco particles and a gum base, wherein the gum base comprises one or more hydrophobic gum base polymers, and wherein the tobacco particles are made from tobacco leaves,
wherein the amount of tobacco particles is between 0.5 and 30% by weight of the chewing gum formulation, wherein nicotine is released from the tobacco particles when chewing the chewing gum formulation, wherein at least 50% by weight of the tobacco particles have a size above 300 μm, and wherein at least 30% of tobacco fibres comprised in the tobacco particles are retained in the chewing gum after the chewing gum has been chewed in vitro in accordance with European Pharmacopeia 4th. ed. 2.9.25 in a pH 7.4 phosphate buffer for 10 minutes.