NANOFIBERS WITH MULTIPLE ALPHA-HELICES BASED ON HAIRPIN-TYPE AMPHIPHILIC PEPTIDES AND THE METHOD FOR PREPARATION THEREOF

摘要

The present invention relates to nanofibers with multiple alpha-helices based on hairpin-type amphiphilic peptides, wherein the hairpin-type amphiphilic peptide includes a hydrophilic region having an alpha-helix structure and a hydrophobic region. The nanofibers with multiple alpha-helices according to the present invention is expected to be utilized in medical fields, such as biosensor materials and therapeutic agents having bioactivity, since the energy is reduced due to the self-assembly through intermolecular attraction when the nanofibers are prepared, the preparation process is environmentally friendly, the strength of the non-covalent bond can be controlled through the control of the ionic strength, and the thermal stability and the alpha-helix stability are excellent.