| 发明名称 | Expression of antibody or a fragment thereof in lactobacillus | ||
| 摘要 | Described herein are methods and compositions for expressing an antibody or a fragment thereof in a microorganism and use of the microorganism to treat or prevent a pathogenic infection in a mammal. | ||
| 申请公布号 | US8853382(B2) | 申请公布日期 | 2014.10.07 |
| 申请号 | US201113814484 | 申请日期 | 2011.08.04 |
| 申请人 | Hera Pharmaceuticals, Inc. | 发明人 | Hammarström Lennart;Marcotte Harold;Alvarez Miguel Angel;Martin Maria Cruz |
| 分类号 | C07H21/04;A61K39/02;A61K48/00;C12N15/74;A61K35/74;C07K16/28;A61K35/00;A61K39/00 | 主分类号 | C07H21/04 |
| 代理机构 | K&L Gates LLP | 代理人 | K&L Gates LLP |
| 主权项 | 1. An expression cassette comprising at least one polynucleotide sequence wherein said polynucleotide sequence is selected from the group consisting of SEQ ID NO:23, SEQ ID NO:24, SEQ ID NO:25, SEQ ID NO:26, and SEQ ID NO:27. | ||
| 地址 | Columbia MD US | ||