Compuesto metanosulfonato de [(2r)-2-(ciclopentilmetil)-3-(2-{5-fluoro-6-[(9as)-hexahidropirazino[2, 1-c][1,4]oxazin-8(1h)-il]-2-metil-4-pirimidinil}hidrazino)-3-oxopropil]hidroxiformamida, forma 1 y forma 2; composicion farmaceutica que los comprende.

摘要

The present invention relates to {2-(alkyl)-3-[2-(5-fluoro-4-pyrimidinyl)hydrazino]-3-oxopropyl}hydroxyformamide compounds of Formula (I): or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, processes for making and use of such compounds in the inhibition of bacterial peptide deformylase (PDF) activity and in treatment methods for bacterial infections.