METHOD FOR ASSESSING ANTI-HERPETIC EFFICACY in vitro OF PHOTODYNAMIC EXPOSURE ON HERPES SIMPLEX VIRUS (HSV)

摘要

FIELD: medicine.SUBSTANCE: method involves photodynamic exposure on a Vero cell culture of HSV-1 and HSV-2 infected African green monkey's kidney, on samples containing HSV-1 and HSV-2 and on a virus progeny; if observing a decrease of virus titre from a reference by 2 and more of lg TCD/0.1 ml in the cell culture, samples containing the viruses, and in the virus progeny, the anti-herpetic action is considered to be effective.EFFECT: using declared method enables more accurate assessment in vitro of the efficacy of the photodynamic therapy to study the mechanisms of various PDT options for the purpose of the further prediction of the PDT efficacy in the herpes-infected patients.3 ex