发明名称 |
N1-BENZO[1,3]DIOXOL-5-YLMETHYL-N2-SUBSTITUTED BIGUANIDE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME |
摘要 |
The present invention relates to an N1-benzo[1,3]dioxol-5-ylmethyl-N2-substituted biguanide derivative expressed in chemical formula 1, to a pharmaceutically acceptable salt thereof, to a preparation method thereof, and to a pharmaceutical composition containing the same as an active ingredient. The N1-benzo[1,3]dioxol-5-ylmethyl-N2-substituted biguanide derivative of the present invention shows superior hypoglycemic action and superior hypolipidemic action even at a lower dosage as compared with conventional drugs, and thus can be used for the prevention and treatment of metabolic syndrome disorders such as diabetes, non-insulin-dependent diabetes, obesity, arteriosclerosis, and the like, or cancer involving P53 gene deficiency. |
申请公布号 |
WO2010044581(A2) |
申请公布日期 |
2010.04.22 |
申请号 |
WO2009KR05855 |
申请日期 |
2009.10.13 |
申请人 |
HANALL PHARMACEUTICAL COMPANY, LTD.;KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;KIM, SUNG WUK;JUN, SUNG SOO;CHEON, HYAE GYEONG;KIM, KWANG ROK;RHEE, SANG DAL;JUNG, WON HOON;LEE, JONG CHEOL |
发明人 |
KIM, SUNG WUK;JUN, SUNG SOO;CHEON, HYAE GYEONG;KIM, KWANG ROK;RHEE, SANG DAL;JUNG, WON HOON;LEE, JONG CHEOL |
分类号 |
C07D317/48 |
主分类号 |
C07D317/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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