| 摘要 |
Disclosed is an anti-TGFbetaRII immunoglobulin single variable domain comprising an amino acid sequence as set forth in SEQ ID NO: 267 having up to 5 amino acid substitutions, deletions or additions, in any combination; wherein the sequence is as disclosed in the specification. Also disclosed are methods of preparation of the disclosed domain and its use in treating tissue fibrosis. |
