| 发明名称 |
Method of Treating a Proliferative Disease |
| 摘要 |
The present invention relates to a method of treating a patient with a serine/threonine kinase inhibitor wherein resistance to the treatment with a serine/threonine kinase inhibitor is suppressed by administering the serine/threonine kinase inhibitor on an intermittent dosing schedule. |
| 申请公布号 |
US2014275136(A1) |
申请公布日期 |
2014.09.18 |
| 申请号 |
US201214355903 |
申请日期 |
2012.11.09 |
| 申请人 |
NOVARTIS AG |
发明人 |
Stuart Darrin;Thakur Meghna Das |
| 分类号 |
A61K31/506 |
主分类号 |
A61K31/506 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a proliferative disease characterized by a mutation in BRAF kinase, which comprises suppressing resistance to treatment with a BRAF inhibitor of the Formula IIby administering the BRAF inhibitor of Formula II on an intermittent dosing schedule. |
| 地址 |
Basel CH |
