| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to the pharmaceutical industry and represents a liquid pharmaceutical composition for improving at least one medical condition requiring administration of an adrenergic compound into an individual; the pharmaceutical composition contains the adrenergic compound, wherein the adrenergic compound is epinephrine or its physiologically acceptable salt, and at least one antioxidant specified in a group consisting of bisulphite, metabisulphite and sulphite compounds, wherein a molar ratio of the adrenergic compound to at least one antioxidant measured as a sulphite equivalent falls within the range of 0.70-1.30 and wherein the pH value of the above liquid composition falls within the range of 2.0-5.0.EFFECT: invention provides higher storage stability with substantially reduced sensitivity to induced light, thermal and oxidative degradation.17 cl, 9 dwg, 3 ex |
