发明名称 |
THERAPEUTIC OR PROPHYLACTIC AGENT FOR DIABETES |
摘要 |
A therapeutic or prophylactic agent for diabetes comprising a thiazolidine derivative as a PPAR-³ agonist as an effective component, which agent shows a reduced side effect of the PPAR-³ agonist, is disclosed. The therapeutic or prophylactic agent for diabetes comprises a particular IP agonist such as beraprost sodium (BPS), and a thiazolidine derivative such as pioglitazone or a pharmaceutically acceptable salt thereof. Since the therapeutic or prophylactic agent of the present invention shows a sufficiently effective hypoglycemic action without being accompanied by side effects characteristic to PPAR-³ agonists (e.g., body weight gain), the agent is useful as a highly safe and effective therapeutic or prophylactic agent for diabetes. |
申请公布号 |
EP2500020(B1) |
申请公布日期 |
2014.09.10 |
申请号 |
EP20100830012 |
申请日期 |
2010.11.12 |
申请人 |
TORAY INDUSTRIES, INC.;THE UNIVERSITY OF TOKYO |
发明人 |
TAKAHASHI,TAKEHIRO;KUMAGAI, HIROKI;KADOWAKI, TAKASHI;KUBOTA, NAOTO;KUBOTA, TETSUYA |
分类号 |
A61K31/4439;A61K31/343;A61P3/04;A61P3/10;A61P43/00 |
主分类号 |
A61K31/4439 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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