Double compartment skincare products comprising avermectin/milbemycin compounds

摘要

Double compartment skincare products confine a first compartment containing an anhydrous composition including an active ingredient, and a second compartment, wherein the active ingredient is selected from among compounds of the avermectin family and compounds of the milbemycin family, and are useful as medicaments for the treatment and/or prevention of dermatological conditions/afflictions.

主权项

1. A single pack skincare product having two compartments:
(a) a first compartment containing a first anhydrous composition comprising, in a pharmaceutically acceptable medium, an active ingredient which is ivermectin in a form which is solubilized in a member selected from the group consisting of polar solvents, oils, amphiphilic solvents and their mixtures, said first anhydrous composition being a solution or an anhydrous gel comprising at least, in percent by weight relative to the total weight of the composition:
(i) from 0.1 to 99.99% of at least one polar solvent for the active ingredient;(ii) gelling agent(s) in an amount of up to 5%;(iii) from 0 to 10% of surfactant(s);(iv) from 0.001 to 50% of active ingredient; and(v) from 0 to 3% of preservative(s), and (b) a second compartment containing a second composition comprising pharmaceutically and/or cosmetically acceptable excipients and which comprise at least a moisturizing compound and/or emollient,as a combination product useful for the treatment of dermatological conditions/afflictions simultaneously, separately or spread out over time, wherein the first and second compartments are the only compartments in the skincare product, and wherein the single pack skincare product is to be marketed.