发明名称 |
Replacement therapy for dental caries |
摘要 |
The invention provides recombinant Streptococcus mutans strains that can be used to improve oral health. An embodiment of the invention provides a method of reducing the incidence or severity of dental caries in a dental caries-susceptible host comprising administering orally to the host an isolated recombinant S. mutans strain of the invention in an amount effective for replacement of dental caries-causing S. mutans host strains in the oral cavity of the host. The isolated recombinant S. mutans strain 10 can be contained in a mouthwash, toothpaste, chewing gum, floss, chewable tablet, food, or beverage. |
申请公布号 |
AU2013226404(A1) |
申请公布日期 |
2014.08.21 |
申请号 |
AU20130226404 |
申请日期 |
2013.02.22 |
申请人 |
THE TEXAS A&M UNIVERSITY SYSTEM;ORAGENICS, INC. |
发明人 |
HILLMAN, JEFFREY D.;SMITH, JAMES LEIF;WILSON-STANFORD, SHAWANDA R. |
分类号 |
C07K14/315 |
主分类号 |
C07K14/315 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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