Vegetable oil composition containing palm mid-fraction fat and method of reducing plasma cholesterol

摘要

A method and composition for reducing the cholesterolemic effect in mammals of ingesting a blended nutritional fat composition containing a palm mid-fraction (PMF) hardstock fat combined with an unsaturated vegetable oil. The composition is solid or semi-solid at 20° C. and fluid at 35° C., and includes between 15% and 45% by weight linoleic acid. The weight ratio of disaturated triglyceride (DST) molecules to trisaturated triglyceride (TST) molecules is greater than 10:1, and the PMF hardstock fat contains approximately 50% to 95% by weight DST molecules, the majority of which contain either palmitic acid or a combination of palmitic and stearic acids at the sn-1 and sn-3 triglyceride positions and either oleic acid or linoleic acid at the sn-2 molecular position.

主权项

1. A method of reducing the plasma LDL cholesterol in a mammalian subject in need thereof without significantly reducing plasma HDL cholesterol in the subject, the method comprising:
providing a blended nutritional fat composition comprising:
at least one triglyceride-based palm mid-fraction fat; andat least one triglyceride-based unsaturated vegetable oil;
wherein the fat portion of the composition contains from 10% to 24% by weight of said at least one palm mid-fraction fat and from 60% to 90% by weight of said at least one unsaturated vegetable oil;wherein the linoleic acid content of the composition is from 15% to 45% by weight based on the total weight of fatty acids in the composition;wherein the composition is solid or semi-solid at 20° C. and fluid at 35° C.; andwherein the composition is substantially free of synthetic trans-fatty acids; and allowing the subject to consume the composition; wherein the composition is consumed regularly by the subject in place of other dietary fat and provides from 10% to 40% of the total daily dietary calories of the subject; wherein the other dietary fat is solid or semi-solid at 20° C.; and whereby the plasma LDL cholesterol of the subject is reduced without significantly reducing plasma HDL cholesterol of the subject.