发明名称 RIBOZYME FOR IDENTIFYING MODIFICATION ON RNA SEQUENCE AND RNA CLEAVAGE METHOD USING SAME
摘要 The hammerhead ribozyme according to the present invention produces a hammerhead ribozyme—target RNA construct by base-pairing with an edited target RNA, and an editing recognition site of the hammerhead ribozyme cleaves the modification site by forming a base pair with the target RNA modification site. The cleavage of the modification site is expected to be applicable to the research and development of new drugs that can be used to prevent or treat diseases caused by the edited target RNA.
申请公布号 US2014228556(A1) 申请公布日期 2014.08.14
申请号 US201214118562 申请日期 2012.05.19
申请人 Fukuoka University 发明人 Fukuda Masatora;Deshimaru Masanobu;Kurihara Kei
分类号 C12N15/113 主分类号 C12N15/113
代理机构 代理人
主权项
地址 Fukuoka JP