| 发明名称 |
COMPOSITIONS AND METHODS FOR GLYCAN SEQUENCING |
| 摘要 |
Compositions and methods directed to a glycan reagent for depolymerization of a glycan having a reducing end, the glycan reagent being represented by the formula MCX, in which M is a glycan coupling group selected from oxylamines and hydrazides; C is a fixed charge group or a basic group having a proton affinity of at least 210 kcal/mol; and X is hydrogen or a free radical initiator chemically coupled to C. |
| 申请公布号 |
US2014227793(A1) |
申请公布日期 |
2014.08.14 |
| 申请号 |
US201414181622 |
申请日期 |
2014.02.14 |
| 申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
Gao Jinshan;Beauchamp Jesse L. |
| 分类号 |
G01N33/50;C07D401/12 |
主分类号 |
G01N33/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A glycan reagent for depolymerization of a glycan having a reducing end, the glycan reagent being represented by the formula MCX, wherein M is a glycan coupling group selected from oxylamines and hydrazides; C is a fixed charge group or a basic group having a proton affinity of at least 210 kcal/mol; and X is hydrogen or a free radical initiator chemically coupled to C. |
| 地址 |
Pasadena CA US |
