The present invention relates to a method of producing a recombinant protein by harvesting a microbial cell broth and adding an amount of a flocculant to achieve an effective particle size distribution. The present invention also relates to a method of clarifying a microbial harvest by adding an amount of a flocculant to achieve an effective particle size distribution.
申请公布号
WO2014118220(A1)
申请公布日期
2014.08.07
申请号
WO2014EP51705
申请日期
2014.01.29
申请人
GLAXO GROUP LIMITED
发明人
CHATEL, ALEX;HOARE, MICHAEL;KUMPALUME, PETER;MOLEK, JESSICA RACHEL;RECK, JASON MICHAEL;WEBER, ANDREW DAVID