DEVICES, SYSTEMS, AND METHODS TO MEASURE PARALLEL TISSUE CONDUCTANCE, LUMINAL CROSS-SECTIONAL AREAS, FLUID VELOCITY, AND/OR DETERMINE PLAQUE VULNERABILITY USING TEMPERATURE

摘要

Devices, systems, and methods to measure parallel tissue conductance, luminal cross-sectional areas, fluid velocity, and/or determine plaque vulnerability using temperature. In at least one embodiment of a method to obtain parallel tissue conductance, the method comprises the steps of inserting at least part of a detection device into a luminal organ, applying current thereto, obtaining a native temperature measurement, injecting a solution of a known conductivity into the luminal organ, detecting a temperature change indicative of the fluid within the luminal organ, measuring an output conductance, and calculating a parallel tissue conductance based upon the output conductance and the conductivity of the injected solution.

主权项

1. A method to obtain conductance data within a luminal organ, the method comprising the steps of:
operating a detection device at least partially positioned within a luminal organ at a first location to obtain a first fluid temperature measurement; detecting a temperature change at the first location using the detection device, the temperature change indicative of an injection of a bolus of a solution having a known conductivity into the luminal organ; and measuring multiple output conductances using at least one impedance electrode of the detection device prior to dilution of the bolus at the first location at least until a threshold temperature is reached.