| 发明名称 |
Antagonists of IL-23P19 for treatement of atopic dermatitis |
| 摘要 |
Nucleic acids encoding mammalian, e.g., primate, receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described. |
| 申请公布号 |
US8795666(B2) |
申请公布日期 |
2014.08.05 |
| 申请号 |
US201313762133 |
申请日期 |
2013.02.07 |
| 申请人 |
Merck Sharp & Dohme Corp. |
发明人 |
Chirica Madaline;Kastelein Robert A.;Moore Kevin;Parham Christi L. |
| 分类号 |
A61K39/00;A61K39/395;C07K16/00 |
主分类号 |
A61K39/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a human subject experiencing atopic dermatitis comprising administering an effective amount of an antagonist antibody that specifically binds to a polypeptide comprising the sequence of SEQ ID NO: 6, or an antigen binding fragment thereof. |
| 地址 |
Rahway NJ US |
