The invention provides sealants wherein biodegradable hydrogels that do not otherwise comprise protein-reactive groups for binding to membranes or tissue are provided said groups optionally through a linker. The linker may be biodegradable and may be biodegradable by an elimination reaction. The invention also provides multilayer gels for drug delivery wherein a porous gel in contact with a tissue or organ to which the drug is to be delivered is protected by a microporous layer from the surrounding bodily fluid.
申请公布号
WO2014116717(A1)
申请公布日期
2014.07.31
申请号
WO2014US12571
申请日期
2014.01.22
申请人
PROLYNX LLC;HENISE, JEFFREY, C.;ASHLEY, GARY, W.;SANTI, DANIEL, V.
发明人
HENISE, JEFFREY, C.;ASHLEY, GARY, W.;SANTI, DANIEL, V.