发明名称 A NEW METFORMIN GLYCINATE SALT FOR BLOOD GLUCOSE CONTROL
摘要 <p>The present invention relates to metformin glycinate salt and pharmaceutical compositions thereof for the treatment of diabetes mellitus. The method includes administration of the metformin glycinate salt by various routes selected from oral, intravenous injectable, intramuscular injectable, nasal, intraperitoneal, or sublingual, in order to achieve a reduction in blood glucose levels. The invention further relates to the synthesis of a new 1,1-dimethylbiguanide glycinate salt, called Metformin Glycinate. The resulting salt exhibits advantages over other metformin salts. These advantages are due, in the first place, to the fact that the glycine counterion exhibits hypoglycemic effects by itself. Moreover, the salt exhibits more rapid absorption, reaching higher plasma concentrations than those produced with metformin hydrochloride.</p>
申请公布号 SI2303838(T1) 申请公布日期 2014.07.31
申请号 SI20080031163T 申请日期 2008.06.26
申请人 LABORATORIOS SILANES, S.A. DE C.V. 发明人 LARA OCHOA JOSE MANUEL FRANCISCO
分类号 主分类号
代理机构 代理人
主权项
地址