发明名称 Use Of Detection Of Aspartate Transaminase And Lactate Dehydrogenase In Early Evaluation Of Clinical Efficacy Of Antitumor Intervention Measure
摘要 The present invention relates to a method for early evaluation of clinical efficacy of antitumor intervention measure, comprising evaluating the efficacy of the antitumor intervention measure by assaying whether the content of a tumor-damaging biomarker(s) in the blood of a patient having tumor rises as compared to the baseline level before treatment within a time window after the patients receives at least one antitumor intervention measure. In preferable embodiments, the tumor-damaging biomarker(s) is selected from a group consisting of Alanine Aminotransferase (ALT), Aspartate Transaminase (AST), Lactate Dehydrogenase (LDH); said tumor is multiple myeloma; said antitumor intervention measure is the administration of CPT alone or the administration of CPT in combination with thalidomide.
申请公布号 US2014206025(A1) 申请公布日期 2014.07.24
申请号 US201114240311 申请日期 2011.08.30
申请人 Yang Shifang;Cui Junsheng;Wei Peng;Zheng Xiangjun;Zhu Bing 发明人 Yang Shifang;Cui Junsheng;Wei Peng;Zheng Xiangjun;Zhu Bing
分类号 G01N33/50 主分类号 G01N33/50
代理机构 代理人
主权项 1. A method for early evaluation of clinical efficacy of an antitumor intervention measure, comprising: evaluating the efficacy of the antitumor intervention measure by assaying whether the content of a tumor-damaging biomarker(s) in the blood of a patient having tumor rises as compared to the baseline level before treatment within a time window after the patients receives at least one antitumor intervention measure.
地址 Beijing CN