发明名称 TRICYCLIC PYRAZOLOPYRIMIDINE DERIVATIVE
摘要 FIELD: chemistry.SUBSTANCE: invention relates to 2-{4-amino-2-[(3-chloro-4-methoxy-5-methylpyridin-2-yl)methyl]-2,7-dihydro-6-thia-1,2,3,5-tetraazabenzo[cd]azulen-8-yl}-N-methylacetamide and its salts, such as hydrobromide, hydrochloride, methane sulfonate, ethane-1,2-disulfonate. The invention also relates to a medication and a pharmaceutical composition based on the said compound and its salts for inhibition of ATP-ase activity of HSP90.EFFECT: novel compound and its salts, which can be applied in medicine for cancer treatment, are obtained.23 cl, 10 ex
申请公布号 RU2520966(C2) 申请公布日期 2014.06.27
申请号 RU20110139157 申请日期 2010.02.24
申请人 DAJITI SANKIO KOMPANI, LIMITED 发明人 OKHKI KHITOSI;OKAJAMA TOORU;IKEDA MASAKHIRO;OTA MASAKHIRO;SIBATA JOSIKHIRO;NAKANISI TOSIJUKI;UEDA JASUSI;SUZUKI NOBUJUKI;MATUURA SINDZI
分类号 C07D495/16;A61K31/519;A61P35/00 主分类号 C07D495/16
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